'''Prote'''ins complement expressed by a gen'''ome''' or tissue --Wilkins et at. 1995 ''BiotechnologyAndGeneticEngineeringReviews'' 12, 19-50

특정개체의 특정상태에서의 모든 [[Proteins]], [[Genome]]이 모든 cell이 가지고 있는 같은 정보임에 비해, [[Proteome]]은 cell specific한 정보이다.

While [[Genome]] is a static repository of information whose contents do not change with time, the [[Proteome]] is highly dynamic, with the subset of [[Proteins]] expressed changing from moment to moment according to the developmental and physiological state of the cell. -- in ProteomicsFromProteinSequenceToFunction

Proteomes change as a function of:
 * time
 * development
 * intracellular
 * extracellular

== Genome vs Proteome ==

|| '''genetic information''' || '''function''' ||
|| [[DNA]] || [[Proteins]] ||
|| 100,000 ~ 120,000 || 500,000 ~ 2,000,000 ||
|| static-no complexity || dynamic-very complex ||
|| amplify || can't amplify ||
|| mapping and sequencing || separation and characterization ||
|| near completion || early stage ||
|| [[Genomics]] || [[Proteomics]] ||


----
[[Gene]]-[[Genome]]-[[Genomics]]와 같은 맥락으로 [[Protein]]-[[Proteome]]-[[Proteomics]]의 개념이다.