A [[Protein]] [[Enzyme]] known to cut a half-[[DNA]] or an [[RNA]] strand at a specific sequence of bases, such as AAAACCTTT X CCC.

It means Restriction Endonuclease.

generates cohesive(sticky) ends
 * EcoRI : G|AATTC - CTTAA|G
 * BamHI : G|GATCC - CCTAG|G
 * BglII : A|GATCT - TCTAG|A

generates flush(blunt) ends
 * BalI : TGG|CCA
 * SmaI : CCC|GGG

RestrictionMap or [[RFLP]] is made by RestrictionEnzyme, [[REBASE]] is its [[Database]]