독성학, Toxicology

1. The adverse effects of chemicals on living organisms
2. Symptoms, mechanisms, treatments and detection of poisoning
3. The relationship between dose and its effects on the exposed organism.

독성물질의 분류

• 표적장기
• 기원
• 작용: [Cancer], mutation, liver injury
• 물리적 상태
• Labeling requirement
• Chemistry
• Toxicity rating
• 작용기전

관련용어

• LD₅₀ : 50%가 사망하는 양 (기울기의 정보가 나타나있지 않다.)

• ED₅₀ : 50%가 효과를 보이는 약의 양

Mechanism of toxicity

• Delivery
• Reaction
• Toxicity
• Repair

독성정도의 평가

• AmesTest