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[Transcription]의 regulation의 한 방식으로써 [DNA]에 특정 [Protein]이 Binding하여 Loop을 생성함으로써 Expression 정도에 영향을 미치는 것을 의미한다.

  • Repression : Lac [Operon] 에서는 repression의 기작으로 사용된다.
  • Enhancement : Sea Urchin의 Endo16의 Regulatory site에서는 SpGCF1이 붙어 DnaLooping을 하는 것으로 추측되며, 그 결과는 weak stimulation of transcription.

DnaLooping.jpg

SeeAlso : [http://bioinfo.sarang.net/moin/wiki/upload/DNALooping_gowers.pdf The geometry of DNA looping by the SfiI restriction enzyme]

DnaLooping (last edited 2011-08-21 16:42:16 by 211)

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