A GeneticBackground technique, and company, to determine risk factors for mental illness, thence to discover therapeutic profiles within patient strata.

The laboratory end of the movement compares changes of gene expression profiles between healthy and diseased brain tissues to those ellicited in cultured neuronal cells or in vivo rat model systems by therapeutically effective psychiatric drugs.

A PolyGenic disease and its multiple drug responses represent "drug signatures". Drug researchers will then seek new small molecules that ellicit gene expression changes similar to the drug signatures and complementary to the disease signatures.

http://www.psygenomics.com/