BioHackersNet|
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| 관련프로그램 | This 3D-structure of [DNA] is formed in the [Telomere] region and inhibit the telemrase. In addition, it has been found in the [Promoter] region of several [Gene]s inclucing OncoGene. Recently, there has been many interests in G-quadruplex stabiling ligands as anti-cancer. G-quadruplex structures in the region of promoter regulate the recruiting of transcription factors, and then transcription of the gene may be blocked. In addition, [RNA] G-Quadruplexes have been found in [HIV] and human. Human RNA G-quadruplexes play roles in regulating RNA-processing like polyadenylation or RnaSplicing. 관련프로그램 및 Database |
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| * [http://bioinformatics.ramapo.edu/grsdb/index.php GRSDB] |
[DNA] 4중나선 구조. G-Quadruplex
This 3D-structure of [DNA] is formed in the [Telomere] region and inhibit the telemrase. In addition, it has been found in the [Promoter] region of several [Gene]s inclucing OncoGene. Recently, there has been many interests in G-quadruplex stabiling ligands as anti-cancer. G-quadruplex structures in the region of promoter regulate the recruiting of transcription factors, and then transcription of the gene may be blocked.
In addition, [RNA] G-Quadruplexes have been found in [HIV] and human. Human RNA G-quadruplexes play roles in regulating RNA-processing like polyadenylation or RnaSplicing.
관련프로그램 및 Database