Diff for "Quadruplex" - BioHackersNet

Differences between revisions 4 and 5

[DNA] 4중나선 구조. G-Quadruplex

This 3D-structure of [DNA] is formed in the [Telomere] region and inhibit the telemrase. In addition, it has been found in the [Promoter] region of several [Gene]s inclucing OncoGene. Recently, there has been many interests in G-quadruplex stabiling ligands as anti-cancer. When the G-quadruplex is formed,RNA polymerase or telomerase can't move forward and then, the product, transcript or telomere which induces cellular transformation, is not generated.

-  ⇤ ← Revision 4 as of 2005-11-25 15:24:04 → 
  Size: 410
  Editor: 211
  Comment:
+   ← Revision 5 as of 2005-11-26 00:07:14 → ⇥
  Size: 594
  Editor: 168
  Comment:
-Deletions are marked like this.
+Additions are marked like this.
 Line 4:
+When the G-quadruplex is formed,RNA polymerase or telomerase can't move forward and then, the product, transcript or telomere which induces cellular transformation, is not generated.