2006-11-03

• [http://www.biologynews.net/archives/2006/11/02/single_molecule_extends_fat_mice_lives_by_reversing_gene_pathways_associated_with_disease_in_obese.html single molecule extends fat mice lives by reversing gene pathways associated with disease in obese] -- Biology News Net

{{| "The "healthspan" benefits we saw in the obese mice treated with resveratrol, such as increased insulin sensitivity, decreased glucose levels, healthier heart and liver tissues, are positive clinical indicators and may mean we can stave off in humans age-related diseases such as type 2 diabetes, heart disease, and cancer, but only time and more research will tell," says Sinclair, who is also a co-founder of Sirtris, a company with an author on this paper and which is currently in a phase 1b trial in humans with diabetes using an enhanced, proprietary formulation of resveratrol. |}}

• : mouse를 가지고 standard diet (SD), high calorie diet (HC), treated with resveratrol (HCR) 이렇게 세그룹으로 나누어서 실험을 진행하였는 데, HC에 비해서 HCR이 거의 SD와 같은 상태를 유지하는 것으로 나타났다. 즉, resveratrol을 투여한 쥐는 fat이 첨가된 고열량 식사를 했지만 건강하고 오랜기간 동안 수명을 유지하였다.

2006-11-01

• VectorNti를 academic version으로는 공짜로 쓸 수 있다고 해서, web site에 들어갔는데, login이나 registration을 하는 페이지로 이동이 안 된다. 어떻게 한거냐?

• [http://www.biologynews.net/archives/2006/10/30/adults_who_go_to_bed_lonely_get_stress_hormone_boost_next_morning.html adults who go to bed lonely get stress hormone boost next morning] -- Biology News Net

{{|In addition to noting that loneliness the night before predicted higher cortisol the next morning, Adam and colleagues found that people who experience anger throughout the day have higher bedtime levels of cortisol and flatter overall levels of the stress hormone, typically considered a risk factor for disorder. "High levels of cortisol in the evening are a kind of biological signature of a bad day," Adam noted.

The study also provided evidence that, in addition to simply being at the mercy of your daily experiences, cortisol also plays a role in influencing them. Individuals with lower levels of cortisol in the morning experienced greater fatigue during the day, a result with potential implications for understanding chronic fatigue.|}}

• : 10월의 마지막 밤을 무사히 보내고, 상쾌한 마음으로 실험실에 왔는데, 뭔 이런 cortisol level 올라가는 내용이라니...

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