In Korean, "막단백질"

막단백질은 일단 단백질과 구별되는 여러가지 특징을 지닌다. 특징들을 나열하면,

• Protein이 생성된 후, 기능을 수행할 위치인 막까지 이동해야 한다.

• 막에 존재하기 위해, 중심부분은 Hydrophobic, 양 끝부분은 Hydrophylic한 성질을 지닌다.

• 따라서, AminoAcid composition상 Hydrophobic AminoAcid 의 함량이 타 Proteins에 비해 높다.

관련정보

논문

Membrane protein folding and oligomerization: the two-stage model (Abstract)

Prediction of the mutation-induced change in thermodynamic stabilities of membrane proteins from free energy simulations - SNU

Determination of peptide oligomerization in lipid bilayers using 19F spin diffusion NMR.

Role of the Degree of Oligomerization in the Structure and Function of Human Surfactant Protein A

Application

Membrane Protein Secondary Structure Prediction Server

Membrane Protein Explorer (MPEx), a tool for exploring the topology and other features of membrane proteins by means of hydropathy plots using thermodynamic principles.

Membrane Proteins of Known 3D Structure

Several Membrane Proteins Libraries - the WARD Lab at the University of Minnesota

Arabidopsis, Oriza Sativa membrane protein database

Helix Packing and Helix Packing Moments in Membrane Proteins

Gerstein Lab - Bioinformatics

Engelman Lab - Membrane

TMSTAT

구조예측 - Classification and Secondary Structure Prediction of Membrane Proteins. AminoAcid Sequence만 갖고 Membrane [Domain]을 찾아주는 사이트입니다.

TMHMM Server v. 2.0 - [HMM]을 이용한 막단백질 예측

TMpred

SeeAlso Membrane Structure and Function