BioHackersNetProtein-tyrosine phosphatase 1B
Genomic Location: 20q13.1-q13.2
AnswerMe : 이 Gene의 Promoter부분에 Transcription을 조절할 수 있는 G-Quadruplex( -(N)nGGG(N)nGGG(N)nGGG(N)nGGG(N)- ) 형성 가능한 sequence가 있을까? --ghost
This Protein plays various roles in metabolic SignalTransduction. PTP1B has been a major target for Type 2 Diabetes and Obesity. Recently, it was reported that PTP1B regulates the development of cellular transformation, Cancer.