Method of ParametricSequenceAnalysis

긴 서열에 대해 Windows size와 step size를 정한다. 그 후 step size만큼 이동하면서, windows size내에 있는 서열들의 특이성을 수치화한다. 이 방법으로 할 수 있는 분석방법들

NucleicAcid

• GC-contents

• GcSkew

• CpG_island

Protein

• Hydrophobisity

Window size

• if too big, the resulting plot is smoothened.
• if too small, the resulting plot fluctuates too much.
• you have to choose a "good" window size somewhere in between these two extremes.

Step size

• doesn't have as dramatic effect as window size
• relatively smaller than the size of the signal. otherwise, you can miss the signal by jumping over it.