The databases SwissProt, TrEmbl, PROSITE, PRINTS, Pfam, and ProDom joined forces to launch an Integrated Resource of ProteinFamily, Domains and Sites, abbreviated InterPro in concept of BioDatabaseIntegration by EBI
http://www.ebi.ac.uk/interpro/
User manual : http://www.ebi.ac.uk/interpro/user_manual.html
ftp site : ftp://ftp.ebi.ac.uk/pub/databases/interpro/
Paper in NucleicAcidsResearch