BioHackersNet|
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| Protease means the [Protein](or [Enzyme]) which degrades (poly)peptides into shorter peptide or [AminoAcid]s. Most frequent example is a digestion enzyme - chymotrypsin or trypsin. | Protease means the [[Protein]](or [[Enzyme]]) which degrades (poly)peptides into shorter peptide or [[AminoAcid]]s. Most frequent example is a digestion enzyme - chymotrypsin or trypsin. |
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| Today, [Protease] is noticed as a drug for several [Virus] disease - [AIDS] , poliomyelitis or plant viral disease. | Today, [[Protease]] is noticed as a drug for several [[Virus]] disease - [[AIDS]] , poliomyelitis or plant viral disease. |
Protease means the Protein(or Enzyme) which degrades (poly)peptides into shorter peptide or AminoAcids. Most frequent example is a digestion enzyme - chymotrypsin or trypsin.
Today, Protease is noticed as a drug for several Virus disease - AIDS , poliomyelitis or plant viral disease.
Protease is classified as nucleophile residue in the active site.
Cleavege site of each protease
Reagent no. |
Reagent |
Cleavage rule |
1 |
Trypsin |
C-term to K/R |
2 |
Lys-C |
C-term to K |
3 |
Arg-C |
C-term to R |
4 |
Asp-N |
N-term to D |
5 |
V8-bicarb |
C-term to E |
6 |
V8-phosph |
C-term to E/D |
7 |
Chymotrypsin |
C-term to F/W/Y/L/M |
8 |
CNBr |
C-term to M |