Diff for "Proteome" - BioHackersNet

Differences between revisions 2 and 4 (spanning 2 versions)

Proteins complement expressed by a genome or tissue --Wilkins et at. 1995 BiotechnologyAndGeneticEngineeringReviews 12, 19-50

특정개체의 특정상태에서의 모든 [Proteins], [Genome]이 모든 cell이 가지고 있는 같은 정보임에 비해, [Proteome]은 cell specific한 정보이다.

While [Genome] is a static repository of information whose contents do not change with time, the [Proteome] is highly dynamic, with the subset of [Proteins] expressed changing from moment to moment according to the developmental and physiological state of the cell. -- in ProteomicsFromProteinSequenceToFunction

Proteomes change as a function of:

time
development
intracellular
extracellular

Genome vs Proteome

genetic information	function
[DNA]	[Proteins]
100,000 ~ 120,000	500,000 ~ 2,000,000
static-no complexity	dynamic-very complex
amplify	can't amplify
mapping and sequencing	separation and characterization
near completion	early stage
[Genomics]	[Proteomics]

[Gene]-[Genome]-[Genomics]와 같은 맥락으로 [Protein]-[Proteome]-[Proteomics]의 개념이다.

-  ⇤ ← Revision 2 as of 2005-10-09 23:16:50 → 
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+   ← Revision 4 as of 2006-02-13 14:38:20 → ⇥
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-Deletions are marked like this.
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+'''Prote'''ins complement expressed by a gen'''ome''' or tissue --Wilkins et at. 1995 ''BiotechnologyAndGeneticEngineeringReviews'' 12, 19-50
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+특정개체의 특정상태에서의 모든 [Proteins], [Genome]이 모든 cell이 가지고 있는 같은 정보임에 비해, [Proteome]은 cell specific한 정보이다.
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+While [Genome] is a static repository of information whose contents do not change with time, the [Proteome] is highly dynamic, with the subset of [Proteins] expressed changing from moment to moment according to the developmental and physiological state of the cell. -- in ProteomicsFromProteinSequenceToFunction

Proteomes change as a function of:
 * time
 * development
 * intracellular
 * extracellular

== Genome vs Proteome ==

|| '''genetic information''' || '''function''' ||
|| [DNA] || [Proteins] ||
|| 100,000 ~ 120,000 || 500,000 ~ 2,000,000 ||
|| static-no complexity || dynamic-very complex ||
|| amplify || can't amplify ||
|| mapping and sequencing || separation and characterization ||
|| near completion || early stage ||
|| [Genomics] || [Proteomics] ||
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+----
[Gene]-[Genome]-[Genomics]와 같은 맥락으로 [Protein]-[Proteome]-[Proteomics]의 개념이다.