Proteins complement expressed by a genome or tissue --Wilkins et at. 1995 BiotechnologyAndGeneticEngineeringReviews 12, 19-50

특정개체의 특정상태에서의 모든 Proteins, Genome이 모든 cell이 가지고 있는 같은 정보임에 비해, Proteome은 cell specific한 정보이다.

While Genome is a static repository of information whose contents do not change with time, the Proteome is highly dynamic, with the subset of Proteins expressed changing from moment to moment according to the developmental and physiological state of the cell. -- in ProteomicsFromProteinSequenceToFunction

Proteomes change as a function of:

• time
• development
• intracellular
• extracellular

Genome vs Proteome

Gene-Genome-Genomics와 같은 맥락으로 Protein-Proteome-Proteomics의 개념이다.