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논문 * [[http://www.yandell-lab.org/publications/pdf/euk_genome_annotation_review.pdf|A beginner's guide to eukaryotic genome annotation]] (Nature reviews, May 2012) |
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관련방법들 | |
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* CpgIsland 탐색 using CpgPlot | * [[CpG_island]] 탐색 using CpgPlot |
Genome서열정보 주석달기.
어떤방법들을 통하여 Genome정보를 해석할 수 있을까.
보통은, GenePrediction --> BLAST, HMMER
관련정보
종에 따른 해석방법
Prokaryotic
TIGR에 보면 미생물 GenomeAnnotation에 관한 체계적인 프로세스가 나와있다.
Euckaryotic
논문
A beginner's guide to eukaryotic genome annotation (Nature reviews, May 2012)
관련방법들
GenePrediction using GenScan, Orpheus
BLASTn in dbEST for coding region and RnaSplicing confirmation
tRNA, rRNA confirmation using tRNAscan-SE
Repeat sequence confirmation using RepeatMasker
regulatory region (TranscriptionFactor) confirmation using TESS
CpG_island 탐색 using CpgPlot
ProteinStructure가 알려진 단백질에 대한 주석