MolecularWeightSearch

http://www.hgmp.mrc.ac.uk/Bioinformatics/Webapp/mowse/

D.J.C. Pappin, P. Hojrup and A.J. Bleasby 'Rapid Identification of Proteins by PeptideMassFingerprint'. Current Biology (1993), vol3, 327-332.

SpectralAlignment후에 점수를 매기는 scoring scheme. (혹은 본 방법을 사용하는 프로그램 및 데이터베이스 명)

Scoring system based on the observed frequency of peptides from all proteins in a Database in a given molecular weight range.

각 Protein의 개별특성들이 반영되지 못한다는 단점을 지닌다. 이의 대안으로 ProFound이용

발전역사 (SeeAlso http://www.matrixscience.com/help/history.html )

1. MOWSE 1 : PeptideMassFingerprint using indexed db

2. MOWSE 2 : Addition for AminoAcid composition / sequence

3. MOWSE 3 : PeptideMassFingerprint, TandemMassSpectrometry fragment ion search, and searches which combined mass data with AminoAcid sequence or composition using FastaFormat database

4. Mascot : Apply to DistributeSystem

CategoryProgramBio